Searchable abstracts of presentations at key conferences in endocrinology

ea0081p516 | Late-Breaking | ECE2022

Myxedema coma: case report and literature review

Cassitas Mendonca Renata , Vilas Boas Laura , Cardoso da Silva Thielsen , Maranho Ribas Laura , Sohn Fagundes Tamila , Elizabeth Cesca Taciane , Paulino Ribeiro Gama Mirnaluci

Introduction: Myxedematous coma is a rare endocrine emergency that settles in the absence of appropriate treatment for hypothyroidism for a long period. The severe and chronic reduction of serum thyroid hormones culminates in the insufficiency of compensatory mechanisms that maintain the physiological homeostasis of the organism. The clinical condition is severe, commonly associated with hypoxemia, hypercapnia, hypothermia, reduced cardiac output, and altered mental status.</p...

ea0081p772 | Late-Breaking | ECE2022

Thionamides-induced agranulocytosis in a patient with previous hematological disease: a case report

Sohn Fagundes Tamila , Vilas Boas Laura , Cardoso da Silva Thielsen , Maranho Ribas Laura , Cassitas Mendonca Renata , Peon Train Nicoluzzi Leticia , Roberta Bianchini Fernandes Maria , Paulino Ribeiro Gama Mirnaluci

Introduction: The treatment of thyroid diseases with thionamides can cause agranulocytosis a potentially fatal side effect. The manifestations resulting from such a condition include, in most cases, infections that, if not treated immediately, have a high risk of septicemia. Therefore, the clinical presentation includes fever of unknown origin and infections such as pneumonia, tonsillitis, and abscesses. Most patients who do not receive immediate medical intervention progress ...